Paraneoplastic dermatomyositis: report of two cases

Abstract

Dermatomyositis is an inflammatory myopathy with an incidence of 0.5-1 case per 100,000 inhabitants. It is characterized by hallmark cutaneus findings and muscle weakness, although we can occasionally find amyo-pathic forms. The association with malignancy has been widely described in the literature, as tumors have been detected in up to a third of the cases. The presence of the anti-TIF-1-gamma antibody presents higher rates of neoplasia compared to other forms without this antibody, so it is manda-tory to do a tumor screening. Next, we present 2 cases of TIF-1-gamma antibody-associated dermatomyositis associated with malignancy.