Metastatic anaplastic oligodendroglioma

Abstract

Metastization from a brain primary tumor is a rare event. The mechanisms of metastization and the best treatment approach are still unknown. Knowledge is, so far, mostly based on case reports. We report a case of a patient with the diagnosis of an anaplastic oligodendroglioma, presenting, 9 months after the brain surgery, with spinal cord compression and pleural effusion. The patient underwent surgery for decompression and local radiotherapy to D12-L5, 30 Gy, 10 fractions and the histology confirmed metastasis of oligodendroglioma. Citology of pleural liquid confirmed the same origin. The patient started temozolomide with good clinical response and stabilization of the disease for 9 months. This is an uncommon case of bone and pleural metastization of anaplastic oligodendroglioma that had a good response to temozolomide in the metastatic setting.